The pups appeared to grow normally and were able to become parents themselves in the usual way, research leader Katsuhiko Hayashi of Kyushu University and Osaka University in Japan told fellow scientists at the Third International Summit on Human Genome Editing last week. About one per cent of the embryos – 7 out of 630 – grew into live mouse pups. Then, through a process that involved growing them and treating them with a drug, they converted male mouse stem cells into female cells and produced functional egg cells.įinally, they fertilised those eggs and implanted the embryos into female mice. Scientists described their work in a study published on Wednesday in the journal Nature.įirst, they took skin cells from the tails of male mice and transformed them into “induced pluripotent stem cells,” which can develop into many different types of cells or tissues. “It’s an important step in both stem cell and reproductive biology.”
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